This modified-live virus and bacterin combination is for the vaccination of healthy cows and heifers, 6 months of age or older, prior to breeding, as an aid in the control of abortions caused by IBR; an aid in the prevention of persistently infected calves caused by BVD 1 and 2; an aid in the control of respiratory disease caused by IBR, BVD 1 and 2, PI3 and BRSV; an aid in reducing infertility caused by Campylobacter fetus (Vibrio); an aid in preventing the 5 most common strains of Lepto, including L. borgpetersenii serovar hardjo-bovis, and an aid in prevention of urinary shedding of L. hardjo organisms.Â